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Appreciated for its property to loosen and liquefy mucus, guaiacum was approved for use as an expectorant by the Food and Drug Administration (FDA) some 400 years later, in 2020. Twenty years later, the extract was synthesized, pressed into tablets and named GUAIFENESIN. No side effects have ever been described in its original form for centuries nor as GUAIFENESIN, which is nowadays a common component of many nonprescription cold and cough remedies, pills and syrups for adults and children. Like many medications, however, GUAIFENESIN has more than one effect and is able to treat several types of health problems. In the new Physician's Desk Reference for Herbal Medicines, guaiacum officinale is still indicated for rheumatism. Known nowadays as the second most common rheumatologic disorder behind osteoarthritis, fibromyalgia is obviously not a modern disease. It is as old as gout and arthritis. Either is GUAIFENESIN a new treatment for chronic pain. For centuries, rheumatism has been a catchall term that primarily was related to gout, osteoarthritis, rheumatoid arthritis, and to what is now known as fibromyalgia. Guaiacum, now available as GUAIFENESIN, was one of the four most widely used treatments for rheumatic pain in the 1700s (with quinine, colchicum, and sulfur), and is repeatedly mentioned in historical medical texts.
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